Current research initiatives in CUBE
At the home pages for the study entities who are forming CUBE you can see a large number of the planned or released studies, please visit:
Please note that not all of the activities in these studies are storing samples into CUBE. This may be because samples are not generated, because of economical restraints, or otherwise. Even when samples have been stored they are usually a limited set of all samples collected, and/or the samples may not yet have been given free for external access by the principal investigator (PI).
The studies, experiments information and samples currently available can be accessed through the CUBE database.
Preconditions for experiments
Here is a short overview of the main issues regarding legal and ethical matters for further information the background document on CUBE can be downloaded here.
According to current Danish regulations the Departments must have a unique approval to house a biobank of samples generated by the department researchers if they wish to store additional human sample material for which it is possible to trace the material back to the donor. CUBE functions as a common repository and will only house samples from departments who have such an approval. An application must therefore be filed in advance and approved by the Danish Data Protection Agency (Danish).
CUBE will not store personal ID numbers (PIDs) for volunteers or any other personal information. The local ethical committees may require that all samples in the Biobank are traceable back to the donor in case the donor at a later stage wishes to withdraw their consent to store samples. In this case the PIs will have to inform the Biobank on which samples to destroy.
According to Danish ethical legislation each human volunteer must give informed consent that their donated samples may be stored in a biobank and used for explorative research by new profiling technologies. This consent is additional to - and separate from - the consent to participate. For information on consent forms, see here (Danish).
The department biobank approval number from the Danish Data Protection Agency must be part of the application for ethical approval in order for the collection to be legal. Otherwise storage of additional samples from an experiment with humans will not be legal. Please note that this is independent of whether researchers want to store their samples with CUBE or in their own freezers.
Storage of animal sample material does not have to comply by the same rules and legislations as for human sample material. Approval from Danish Data Protection Agency is not necessary. However, an application to ‘Dyreforsøgstilsynet' must be filed in advance and approved before commencing experiments (more information (Danish)).